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Health & Wellness

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By Kyle Marie McMahon and Dr. Sarah Maddison |

The Wellness Edit: Navigating Women’s Health with Dr. Maddison Welcome to our new recurring series dedicated to the complexities of the female body. In a world of “wellness” hype and conflicting online advice, we are partnering with local expert Dr. Sarah Maddison to bring you clear, evidence-based, and personable insights into the health topics that matter most to our readers. From hormonal shifts to preventative care, consider this your go-to resource for
navigating every life stage with confidence and clarity.

There’s a specific kind of lifestyle gaslighting we women tend to do to ourselves in our late 30s and 40s. We blame the back-to-back meetings, the third cup of coffee, or the general chaos of a busy life for why we suddenly feel … off. We’ve been conditioned to wait for a dramatic hot flash before we even consider the word perimenopause, but the reality is usually much quieter, much earlier, and far more complex than a single symptom.

In our inaugural Wellness Edit—a new recurring series where we tackle the health topics that actually impact our daily lives—we’re stripping away the clinical jargon and the hushed tones. We’re starting with the transition that touches everything from our sleep to our sense of self, yet remains one of the most misunderstood chapters of the female experience. To help us navigate the flickering lights of hormonal change with actual science and a much-needed reality check, we sat down with Dr. Maddison to get the answers we’re usually only searching for in the middle of the night.

What are the “invisible” early signs of perimenopause that women in their late 30s or early 40s often overlook?

Perimenopause has a sneaky way of arriving long before your periods send an official notice. In your late 30s or early 40s, the subtle clues are often initially blamed on stress, aging, or that second glass of wine. Sleep is usually the first to go—waking up at 3 a.m. for no apparent reason and lying there wide-eyed while you ruminate over schedules and to-do lists. Anxiety may creep in, patience runs thinner, and suddenly, multitasking feels more like multi-forgetting. Workouts seem harder, recovery slower, and weight has an annoying tendency to migrate to your midsection without permission. You might also notice shorter cycles, heavier periods, or PMS that feels more dramatic than it used to. Even alcohol can betray you by ruining your sleep or delivering a disproportionate hangover. None of these signs scream “perimenopause,” but together they’re often the body’s quiet hint that hormonal fluctuations have entered the chat.

How can a woman distinguish between high-stress burnout and actual hormonal shifts?

Distinguishing high-stress burnout from hormonal shifts can feel a bit like solving a mystery where the suspects—stress, sleep deprivation, and hormones—are all suspiciously present. Burnout usually tracks closely with life circumstances: a brutal work stretch, caregiving overload, or months of running on caffeine and determination. When the stress improves, the symptoms often improve too. Hormonal shifts, on the other hand, tend to follow an independent
path of destruction. If sleep suddenly falls apart (hello, 3 a.m. wake-ups), anxiety spikes for no obvious reason, periods change, or PMS becomes dramatically more theatrical, hormones may be quietly involved. Of course, the plot twist is that stress and hormones feed off one another, each making the other louder. If symptoms persist despite rest, stress reduction, and good habits, it’s worth discussing with a clinician. Sometimes the body isn’t burned out—it’s just entering a new hormonal chapter.

Photo by StockAdobe.com/Monkey-Business.

Is there a specific medical test to “confirm” you’ve started the transition, or is it based entirely on symptoms?

If you’re hoping for a simple lab test that definitively announces, “Congratulations, you’ve entered perimenopause,” unfortunately, there’s not one. Hormones during this transition behave less like a steady dimmer switch and more like a flickering light—estrogen can swing dramatically from week to week, or even day to day. That means common blood tests like follicle-stimulating hormone (FSH) or estradiol may look completely “normal” even when the transition has already begun. For that reason, clinicians usually diagnose perimenopause based primarily on symptoms and cycle changes: sleep disruption, mood shifts, brain fog, heavier or shorter cycles, and the occasional middle-of-the-night existential wake-up call. Lab tests can still be useful to rule out other issues—like thyroid disease or anemia—but they rarely provide a definitive yes-or-no answer. In other words, perimenopause is less a lab result and more a pattern your body gradually reveals over time.

How long does the perimenopause phase typically last before reaching full menopause?

Perimenopause isn’t a quick pit stop—it’s more like a long, winding on-ramp. For most women, the transition lasts about 4–8 years before reaching menopause, which is officially defined as 12 consecutive months without a menstrual period. For some, it may be shorter; for others, especially if symptoms start in the late 30s, it can stretch closer to a decade. Early on, cycles may still look fairly regular while subtle symptoms creep in—sleep changes, mood shifts, or brain fog. As the transition progresses, periods often become more unpredictable: closer together, farther apart, heavier, lighter, or occasionally disappearing for a few months just to keep things interesting.

The average age of menopause in the United States is about 51, but the runway leading up to it varies widely. In other words, perimenopause isn’t a single moment—it’s a gradual hormonal transition where the body slowly recalibrates before reaching menopause.

Photo by Stock.Adobe.com/Studio Romantic.

What is the one thing you wish women knew about this transition before it actually starts?

The one thing many clinicians wish women knew is that perimenopause often starts much earlier—and much more quietly—than people expect. Most women are taught to associate menopause with hot flashes in their 50s, but the hormonal transition can begin in the late 30s or early 40s, and the earliest signs are rarely dramatic. Instead, it may show up as disrupted sleep, rising anxiety, brain fog, heavier periods, or feeling like your usual stress tolerance has mysteriously vanished. Because these symptoms are subtle, women often blame themselves—thinking they’re just tired, overwhelmed, or somehow “not handling things as well.” In reality, fluctuating hormones can play a major role.

Understanding that this phase exists—and that these changes are common—can be incredibly empowering. It helps women seek the right information, advocate for themselves in medical settings, and make supportive lifestyle or treatment choices earlier rather than feeling confused or dismissed. That said, avoid the pitfall of blaming everything you don’t like about the ways our bodies change during perimenopause/menopause, because unhealthy lifestyle habits like an unbalanced diet, alcohol use, poor sleep habits, or a lack of regular exercise will contribute to these changes as well.

How do you recommend perimenopausal women speak with their health care provider, especially one who seems dismissive about their symptoms?

If a woman feels dismissed when discussing perimenopause, the most helpful strategy is to approach the conversation prepared and armed with specific concerns. Instead of saying “I just don’t feel like myself,” it can help to bring a short list of concrete symptoms—changes in sleep, mood, cycle length, bleeding patterns, brain fog, or anxiety. That kind of detail gives a provider something measurable to work with.

It’s also perfectly reasonable to ask direct questions like, “Could these symptoms be related to perimenopause?” or “What options are available to manage them?” If the concerns are still brushed aside, seeking a second opinion can be valuable. Not every clinician has the same training or comfort level with menopause care.

Ultimately, women should feel heard and supported. If a provider consistently minimizes symptoms, it may simply be a sign that it’s time to find someone with more experience or interest in midlife women’s health. The Menopause Society provides a list of providers who are certified menopausal care practitioners. In addition to having passed examinations demonstrating their knowledge, this designation shows they are committed to caring for women during this
time—a strong indicator that they will address your concerns.

Dr. Maddison is a board-certified physician dedicated to providing comprehensive, compassionate care for women in the Triangle. With a specialized focus on midlife health and hormonal transitions, she is a member of The Menopause Society and is committed to empowering her patients through evidence-based medicine and personalized wellness strategies. When she isn’t in the clinic, she is a vocal advocate for women’s health education, helping patients navigate the complexities of perimenopause and beyond with clarity and confidence.

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